what in the hell do you mean you never use the mouse? you type in cordinates my hand? learn the osnap, change your aperature, change your crosshairs to take up full screen. 99% of shortcuts can be done via the command line (edit your acad.pgp file to customize your commands, mine are all set the left side of my keyboard so they can all be typed with my left hand... all are shortened too). keyboard is good for cordinates if you're pointing at a certain angle and type in 8 feet or whatever.
the grid is useless in 90% of all applications, but if you want to use it, don't forget to set your limits.
learn to customize your toolbar.
learn paperspace.
what type of cad work is it going to be?